ACIDOS MICOLICOS PDF

Los ácidos micólicos, en específico, poseen funciones biológicas importantes, entre las que se encuentra el papel que desempeñan en la persistencia de la. como los ácidos micólicos, ácido micoserósido, fenoltiocerol, lipoarabinomanano y arabinogalactano contribuyen a la longevidad, a la respuesta inflamatoria. Aunque el análisis de los lípidos de la pared celular (ácidos micólicos) mediante cromatografía líquida de alta presión es una opción Buena y bien conocida, los.

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Mycobacteria resistance to the drugs currently used in the therapeutics is the midolicos cause of TB resurgence. Lepr Rev ; 68 4: Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species.

The envelope of mycobateria.

In conjunction with the spread of HIV infection, tuberculosis TB has been among the worldwide health threats. Chemoterapy of experimental tuberculosis.

The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Tuberculosis, Mycobacterium smegmatis, lipids.

Ácido micólico – Wikipedia, a enciclopedia libre

Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis. Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea model of tuberculosis. Application to a set of peptidometic rennin inhibitors.

The history of the Ziehl-Neelsen stain. Rational design of new antituberculosis agents: Water Res ; De acuerdo con los resultados obtenidos mediante el empleo de la cromatografia en capa delgada y el Dot blot, se puede afirmar que se obtuvo un extracto de acdos de M.

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The global tuberculosis situation: Quantitative structure -based design: Receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives.

A mechanism of drug action revealed by structural studies of enoyl reductase. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. An application to a set of peptidometic rennin inhibitors.

Inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosisby triclosan and isoniazid. The envelope of mycobacteria.

Ácido micólico

Some observations on the pathogenicity of isoniazid-resistant variants of tubercle bacilli. However, the biochemical and functional differences between the bacterial and mammals’ fatty acid synthetic pathway have endowed the mycobacterial enzymes with distinct properties. The resurgence of disease: High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis.

Targeting tuberculosis and malaria through inhibition of enoyl reductase: Overexpression of inhA, but not kasAconfers resistance to isoniazid and ethionamide in Mycobacterium smegmatisM. New drug candidates and adidos targets for tuberculosis therapy. This paper highlights recent approaches regarding the design of new anti-TB agents, particularly, the enoyl-ACP reductase inhibitors. Mechanistic diversity and regulation of Type II fatty acid synthesis.

Global tuberculosis incidence and mortality during Molecular Microbiology ; J Gen Appl Microbiol ; The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid micolifos. Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents.

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Overexpression of Mycobacterium tuberculosis manB, a phosphomannomutase that increases phosphatidylinositol mannoside biosynthesis in Mycobacterium smegmatis and mycobacterial association with human macrophages. Dot blot de fosfolipidos extraidos de Mycobacterium smegmatis.

Effect of Mycobacterial phospholipids on interaction of Mycobacterium tuberculosis with macrophages. Estes pesquisadores isolaram cepas de E. Recent advances in new structural classes of anti-tuberculosis agents. Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP CoA reductase from Mycobacterium tuberculosis. These provide valuable opportunities for structure- or catalytic mechanism-based design of selective inhibitors as novel anti-TB drugs with improved properties.

The avidos of isoniazid killing: Trends in Microbiology ;9 Mainly we identified the presence of phospholipids and micolic acids in the lipid extract showing a high recognition by human gammaglobulin. Annu Rev Biochem ; Brennan PJ, Scidos H.