Inhibitor of cathepsins B and L; also thought to inhibit calpain. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A (Cat. Keywords: E 64d, E 64d supplier, lysosomal, proteases, inhibitors, inhibits, cathepsins. Cell-permeable, ethyl ester of Ec. The ester is hydrolyzed by intracellular esterases to produce Ec. Inhibits calpain and cathepsins B, H, and L. Inhibits . Membrane-Permeant Cysteine Protease Inhibitor E64d. S. Eksi,1 B. Czesny,1 G.- J. . or without protease inhibitors, M E64d (Sigma, St Louis, MO), 10 M.

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Since degradation was still observed, calpain protease was eliminated as the cause of ER degradation. Volume to add to vial ml ul. Have you used E 64d? View all Cathepsin Inhibitors.

E-64-d (CAS 88321-09-9)

New Gene Target to Prevent Obesity. Kim et al Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Inhibits degradation of autophagic cargo r64d autophagolysosomes. Submit a review and receive an Amazon gift card. How to Minimize Photobleaching.

There are currently no reviews for this product. Flying Start New Lab Program. Preparing Stock Solutions The following data is based on the product molecular weight For Research Use Only.

Cathepsin inhibitor; interferes with autolysosomal 6e4d. References References are publications that support the biological sigmaa of the product. Batch specific molecular weights may vary from batch to batch due e6d4 solvent of hydration, which will affect the solvent volumes required to prepare stock solutions. The email address or password you have entered is incorrect. The technical data provided above is for guidance only.


See how others have used Ed. Ed scA 5 mg. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more. I am inquiring to see if the product below is available for shipping immediately upon ordering. Reviews for E 64d There are currently no reviews for this product. Published data Date published: The Journal of biological chemistry. Create an account quickly and easily with your preferred social network account.

Ed | CAS | SCBT – Santa Cruz Biotechnology

Literature in this Area Tocris offers the following scientific literature in this area to showcase our products. Proteomic analysis of silenced cathepsin B expression suggests non-proteolytic cathepsin B functionality: Rated 5 out of 5 by NZ from This drug exerts its d64d pretty well This drug exerts its function pretty well in autophagy induction.

Email address already exists, please enter a new valid email address. Cell culture, Abstract. Please sign in using your account on one of the following social networks. Journal of immunology Baltimore, Md. Volume nanoliter microliter milliliter liter.

E 64d Supplier | CAS | E64d | Tocris Bioscience

Mass in vial mg ug ng. Concentration 2 femtomolar picomolar nanomolar micromolar millimolar molar. Fatty acids increase adiponectin secretion through both classical and exosome pathways: By signing up, you indicate that you have read and agree to the terms in our privacy policy. The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.


For batch specific data refer to the Certificate of Analysis. Mass picograms nanograms micrograms milligrams grams kilograms. e64s

Volume 1 nanoliter microliter milliliter liter. Flow Cytometry Spectra Viewer. Why create an account? E 64d, E 64d supplier, lysosomal, proteases, inhibitors, inhibits, cathepsins, autophagy, autolysosomal, digestion, E64d, Autophagy, Calcium-Sensitive, Proteases, Cathepsin,Tocris Bioscience.

The ester is hydrolyzed by intracellular esterases to produce Ec. Privacy and Cookie Policy Site Map. Click on the entry to view the PubMed entry. Creating an account with us makes your shopping experience much easier and faster.

Citations 1 to 6 of 6 total Display: Skip to main content. Exercise Can Reprogram the Brain. Ed, sc, is a white solid.